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Quantifying Argonaute 2 (Ago2) expression to stratify breast cancer.

M C Casey1, A Prakash2, E Holian3

  • 1Discipline of Surgery, School of Medicine, Lambe institute for Translational Research, National University of Ireland, Galway, Ireland.

BMC Cancer
|July 21, 2019
PubMed
Summary

Argonaute-2 (Ago2) protein is often low in breast cancer, but its expression levels and localization can help predict subtypes and improve diagnostic accuracy. Further research into Ago2 dysregulation is needed for subtype-specific insights.

Keywords:
Ago2AmplificationArgonaute 2BiomarkerBreastCancerCytoplasmicDFSDiseaseEIF2C2ExpressionGeneIHCIntensityMidbodyPatternRFSRelapseStainingSurvivalTumourmRNAmiRNAmicroRNA

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