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Related Concept Videos

Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

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Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation01:30

Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation

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Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
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Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

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Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
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Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

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Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
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Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
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Second Asian Consensus on Irritable Bowel Syndrome.

Kok Ann Gwee1, Sutep Gonlachanvit2, Uday C Ghoshal3

  • 1Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, and Gleneagles Hospital, Singapore.

Journal of Neurogastroenterology and Motility
|July 23, 2019
PubMed
Summary
This summary is machine-generated.

This Asian consensus update on irritable bowel syndrome (IBS) highlights its gut-brain interaction basis and effective new treatments like specific diets and probiotics for better patient management.

Keywords:
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Area of Science:

  • Gastroenterology
  • Gut-Brain Axis Research
  • Public Health

Background:

  • Irritable Bowel Syndrome (IBS) understanding has advanced significantly, with new treatments emerging.
  • The Rome IV guidelines (2016) and increasing Asian data necessitate an updated consensus.
  • This initiative addresses the need for current Asian-specific IBS guidelines.

Purpose of the Study:

  • To update the Asian consensus on Irritable Bowel Syndrome (IBS).
  • To review current knowledge on IBS symptoms, epidemiology, pathophysiology, diagnosis, and management in Asia.
  • To provide evidence-based recommendations for IBS care in the Asian region.

Main Methods:

  • Key opinion leaders from Asian countries formed four teams focusing on specific IBS themes.
  • A modified Delphi method was employed for consensus development.
  • Review encompassed symptoms, epidemiology, pathophysiology, diagnosis, investigations, and treatment strategies.

Main Results:

  • Thirty-seven consensus statements were formulated.
  • Asian data reinforce IBS as a gut-brain interaction disorder.
  • Socio-cultural factors in Asia influence IBS and upper GI symptom overlap.
  • Novel treatments including low FODMAP diets, probiotics, antibiotics, and secretagogues show efficacy.

Conclusions:

  • Comprehensive evaluation and holistic management are recommended for all functional gastrointestinal disorder patients.
  • Physicians should adopt a positive outlook towards IBS treatment outcomes.
  • This consensus provides a framework for improved IBS care in Asia.