Related Experiment Video

Updated: Jan 21, 2026

Defining the Role Of Language in Infants' Object Categorization with Eye-tracking Paradigms
07:31

Defining the Role Of Language in Infants' Object Categorization with Eye-tracking Paradigms

Published on: February 8, 2019

7.2K

Objective measurement of nocturnal cough in infants with acute bronchiolitis

Kota Hirai1, Mariko Nukaga2, Hideyuki Tabata2

  • 1Department of Pediatrics, Tokai University Hachioji Hospital, 1838, Ishikawa, Hachioji, Tokyo, 192-0032 Japan.

Respiratory Investigation
|July 23, 2019
PubMed

Insights

Children with respiratory syncytial virus (RSV)-induced acute bronchiolitis and asthma exacerbation have similar nighttime cough counts. However, acute bronchiolitis lacks the characteristic cough pattern seen in asthma patients.

Area of Science:

  • Pediatric respiratory medicine
  • Biomedical engineering
  • Sleep science

Background:

  • Objective measurement of cough severity and nocturnal patterns can aid pediatric respiratory disease treatment.
  • Respiratory syncytial virus (RSV)-induced acute bronchiolitis and asthma exacerbation are common in children, often presenting with cough.

Purpose of the Study:

  • To objectively measure and compare cough severity and nocturnal cough patterns in children with acute bronchiolitis and asthma exacerbation.
  • To differentiate between cough characteristics in these two pediatric respiratory conditions.

Main Methods:

  • Developed and utilized an original recording system with a microphone and accelerometer to capture coughs in children.
  • Analyzed cough data using customized software, measuring cough counts in 30-minute intervals.
  • Compared cough data from 20 children with acute bronchiolitis to 16 infants with asthma exacerbation.

Main Results:

  • Cough counts were similar between children with acute bronchiolitis (median: 108.0/night) and asthma exacerbation (median: 119/night).
  • Infants with asthma exacerbation showed significantly increased cough frequency upon falling asleep and waking up compared to midnight (p < 0.001).
  • This characteristic overnight cough pattern was not observed in infants with acute bronchiolitis.

Conclusions:

  • The number of coughing events in acute bronchiolitis is comparable to acute asthma exacerbation.
  • Acute bronchiolitis does not exhibit the distinct overnight cough pattern observed in asthma exacerbation.
  • Objective cough monitoring can help differentiate between pediatric respiratory conditions.
Abstract

Keywords:
Acute bronchiolitisCoughCough counterInfantRespiratory Syncytial virus

More Related Videos

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants11:39

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Published on: March 14, 2013

21.0K
Electrophysiological Measurements and Analysis of Nociception in Human Infants09:18

Electrophysiological Measurements and Analysis of Nociception in Human Infants

Published on: December 20, 2011

17.6K

Related Concept Videos

Potential Due to a Polarized Object01:29

Potential Due to a Polarized Object

A neutral atom consists of a positively charged nucleus surrounded by a negatively charged electron cloud. When placed in an external electric field, the external electric force pulls the electrons and nucleus apart, opposite to the intrinsic attraction between the nucleus and the electrons. The opposing forces balance each other with a slight shift between the center of masses of the nucleus and the electron cloud, resulting in a polarized atom. On the other hand, a few molecules, like water,...
745
Potential Due to a Magnetized Object01:24

Potential Due to a Magnetized Object

Magnetic dipoles in magnetic materials are aligned when placed under an external magnetic field. For paramagnets and ferromagnets, dipole alignment occurs in the direction of the magnetic field. However, the dipoles align opposite to the field in the case of diamagnets. This state of magnetic polarization due to the external field is called magnetization. Magnetization is defined as the dipole moment per unit volume. It plays a similar role to polarization in electrostatics.
The vector...
768
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
262
Moment of Inertia of Compound Objects01:07

Moment of Inertia of Compound Objects

The moment of inertia is a quantitative measure of the rotational inertia of an object. It is defined as the sum of the products obtained by multiplying the mass of each particle of matter in a given body by the square of its distance from the axis. The total moment of inertia for compound objects can be found by determining and adding the moment of inertia of individual components together.
Consider a child of mass (mc) 25 kg standing at a distance (rc) of 1 m from the axis of a rotating...
7.5K
Gravitational Potential Energy for Extended Objects01:07

Gravitational Potential Energy for Extended Objects

Consider a system comprising several point masses. The coordinates of the center of mass for this system can be expressed as the summation of the product of each mass and its position vector divided by the total mass:
1.9K
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
4.0K