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The bright choroid plexus on MR: CT and pathologic correlation.

D B Hinshaw1, J L Fahmy, N Peckham

  • 1Section of Magnetic Resonance Sciences, Loma Linda University, CA 92354.

AJNR. American Journal of Neuroradiology
|May 1, 1988
PubMed
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Bright choroid plexus glomera on MRI may indicate early xanthogranulomata. These findings are typically benign but require differentiation from other potential lesions.

Area of Science:

  • Neuroradiology
  • Pathology

Background:

  • Choroid plexus glomera can appear unusually bright and enlarged on T2-weighted MRI sequences.
  • Incidental findings prompt further investigation into their nature and significance.

Purpose of the Study:

  • To investigate the characteristics and pathological basis of bright choroid plexus glomera identified on MRI.
  • To determine the clinical significance and differential diagnoses of these findings.

Main Methods:

  • Retrospective review of MR imaging in 14 patients with incidental findings and 167 additional patients.
  • Analysis of CT scans for correlation with MR findings.
  • Autopsy examination of 52 choroid plexus glomera for pathological correlation.

Main Results:

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  • 39.5% of 167 patients exhibited bright choroid plexus glomera on T2-weighted MRI.
  • CT scans revealed nonenhancing central regions with peripheral calcifications in most bright glomera.
  • Autopsy findings in eight glomera showed lipid deposits, microcysts, and calcifications consistent with early xanthogranulomata.

Conclusions:

  • Bright and enlarged choroid plexus glomera on MRI are often associated with early xanthogranulomatous changes.
  • These pathological changes are generally of low clinical significance.
  • It is crucial to differentiate these findings from other lesions that may mimic bright or enlarged choroid plexus glomera on MRI.