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Nanocatalytic Medicine.

Bowen Yang1,2, Yu Chen1, Jianlin Shi1

  • 1State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.

Advanced Materials (Deerfield Beach, Fla.)
|July 23, 2019
PubMed
Summary
This summary is machine-generated.

Nanocatalytic medicine integrates catalysis and medicine using nanomaterials for enhanced therapeutic effects. This field leverages nanocatalysts to improve treatment efficacy and reduce side effects in theranostics.

Keywords:
catalysisnanocatalystsnanomedicinereactionstherapeutics

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Catalysis

Background:

  • Catalysis and medicine traditionally operate as distinct fields.
  • Nanochemistry advances enable in vivo application of nanocatalysts (nanozymes, photocatalysts, electrocatalysts).
  • Biomedical applications of nanocatalysts are rapidly expanding, leading to the concept of nanocatalytic medicine.

Purpose of the Study:

  • To introduce and define the emerging field of nanocatalytic medicine.
  • To elucidate the rationale behind constructing nanocatalytic medicine based on catalytic reaction factors.
  • To present recent advances and discuss mechanisms of nanocatalytic systems in theranostics.

Main Methods:

  • Review of recent advances in biomedical applications of nanocatalysts.
  • Analysis of catalytic reaction factors (catalysts, energy input, reactant) for nanocatalyst design.
  • Discussion of mechanisms for conferring theranostic functions to catalytic nanosystems.

Main Results:

  • Nanocatalysts can initiate catalytic reactions and modulate biological microenvironments in vivo.
  • High catalytic efficiency and selectivity translate to high therapeutic efficacy and mitigated side effects.
  • Nanocatalytic medicine offers optimized therapeutic outcomes through steered catalytic reactions.

Conclusions:

  • Nanocatalytic medicine represents a significant subdiscipline in nanomedicine.
  • This emerging field translates chemical catalysis principles into advanced theranostic applications.
  • Catalytic therapeutic modalities are expected to play an increasingly important role in nanomedicine.