Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

59.5K
Overview
59.5K
Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

10.3K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
10.3K
Outcomes of Glycolysis01:13

Outcomes of Glycolysis

106.8K
Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
106.8K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

1.4K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.4K
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

3.7K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
3.7K
Liver Histology01:27

Liver Histology

4.1K
The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
4.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

CD4<sup>+</sup>CD25<sup>+</sup> regulatory T cells circumstantially initiate transplant rejection through CXCL15/neutrophil axis.

Communications biology·2026
Same author

Beyond Breathing: Lung as a Sensory Organ A Report from the NHLBI Workshop on Lung Sensing and its Implication in Diseases.

American journal of respiratory cell and molecular biology·2026
Same author

Aerial drones for graft transport - ready for takeoff?

Transplant international : official journal of the European Society for Organ Transplantation·2026
Same author

Beyond a Biomarker: Investigations of a Proinflammatory Role for Cell-Free DNA in Liver Transplant Ischemia and Reperfusion.

Transplant international : official journal of the European Society for Organ Transplantation·2026
Same author

High Humidity Exacerbates Psoriasiform Skin Disease Relapse by Increasing Tissue-Resident Memory T Cells via Altering Skin Microbiota.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Pancreas Transplantation in the Modern Era: Observations and Implications of Donor Pancreas Extraction Time.

Clinical transplantation·2026

Related Experiment Video

Updated: Jan 21, 2026

A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes
07:37

A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes

Published on: October 28, 2021

3.4K

De-bugging the system: could antibiotics improve liver transplant outcomes?

Jonathan S Bromberg1,2,3, Joseph R Scalea1,2,3, Emmanuel F Mongodin1,2,4

  • 1Department of Surgery.

The Journal of Clinical Investigation
|July 23, 2019
PubMed
Summary
This summary is machine-generated.

The recipient

More Related Videos

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels
08:37

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels

Published on: July 3, 2025

754
Author Spotlight: Advancements and Challenges in Machine Perfusion for Liver Transplantation
05:25

Author Spotlight: Advancements and Challenges in Machine Perfusion for Liver Transplantation

Published on: June 14, 2024

984

Related Experiment Videos

Last Updated: Jan 21, 2026

A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes
07:37

A Rat Lung Transplantation Model of Warm Ischemia/Reperfusion Injury: Optimizations to Improve Outcomes

Published on: October 28, 2021

3.4K
Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels
08:37

Liver Cold Storage and Transplantation in the Cold-Adaptive Daurian Ground Squirrels

Published on: July 3, 2025

754
Author Spotlight: Advancements and Challenges in Machine Perfusion for Liver Transplantation
05:25

Author Spotlight: Advancements and Challenges in Machine Perfusion for Liver Transplantation

Published on: June 14, 2024

984

Area of Science:

  • Transplantation immunology
  • Microbiome research
  • Gastroenterology

Background:

  • Organ transplantation is a vital treatment for end-stage organ failure.
  • Initial allograft function is crucial for successful transplant outcomes.
  • Graft dysfunction, including delayed graft function and primary nonfunction, remains a significant clinical challenge.

Purpose of the Study:

  • To investigate the role of the recipient's microbiome in liver transplant graft function.
  • To evaluate the impact of antibiotic pretreatment on graft outcomes in liver transplantation.

Main Methods:

  • Utilized a mouse model of liver transplantation.
  • Conducted studies on human liver transplant recipients.
  • Assessed graft function following interventions related to the microbiome.

Main Results:

  • Demonstrated a link between the recipient's microbiome and initial liver allograft function.
  • Showcased the beneficial effects of antibiotic pretreatment in improving graft function in both preclinical and clinical settings.

Conclusions:

  • The recipient microbiome influences early liver allograft function.
  • Antibiotic pretreatment represents a promising strategy to enhance outcomes in liver transplantation.