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    This study introduces a novel Region and Edge Synergetic Level Set (RELS) framework for improved image segmentation. RESLS enhances accuracy and efficiency by unifying region and edge information through a normalized intensity indicator function.

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    Area of Science:

    • Computer Vision
    • Medical Imaging
    • Image Processing

    Background:

    • Active contour models with level set evolution are widely used for image segmentation.
    • Hybrid models combining region and edge information improve performance but lack theoretical foundation for term collaboration.
    • Existing hybrid models face challenges in weight coefficient selection and multi-modality accommodation.

    Purpose of the Study:

    • To propose a novel Region and Edge Synergetic Level Set (RELS) framework.
    • To establish a theoretical foundation for the collaboration between region and edge information in image segmentation.
    • To develop a method for reliably selecting energy term weights and improving segmentation performance.

    Main Methods:

    • Developed the RESLS framework incorporating a normalized intensity indicator function.
    • Embedded region information into an edge-based model for seamless integration.
    • Deduced a global optimization condition to constrain energy weights.
    • Demonstrated generality using representative and state-of-the-art models.

    Main Results:

    • The RESLS framework enables reliable selection of weighting parameters guided by the optimization condition.
    • Segmentation accuracy, robustness, and computational efficiency were improved compared to component models.
    • The normalized intensity indicator function facilitates the embedding of region information into edge-based models.

    Conclusions:

    • RELS provides a robust and theoretically grounded approach for hybrid level set image segmentation.
    • The proposed framework offers improved performance and adaptability across different imaging modalities.
    • This method addresses key limitations in existing hybrid active contour models.