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Thiol-sensitive promoters of Escherichia coli
G T Javor1, C D Stringer, J Ryu
1Department of Microbiology, Loma Linda University School of Medicine, California 92350.
Journal of Bacteriology
|July 1, 1988
Abstract:
Mu dX(lac) insertion mutants of Escherichia coli CSH50 in which the expression of the lacZ gene was sensitive to the presence of exogenous 1-thioglycerol or dithiothreitol were isolated. Both stimulatory and inhibitory mutants were found. The existence of several thiol-sensitive promoters suggests that exogenous thiols may provoke global stress responses in E. coli.