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Phospholipid variation in acute ethanol intoxication in rats
I Boerescu1, N Gheorghe, I Boroş
1D. Danielopolu Institute of Normal and Pathological Physiology, Bucharest, Romania.
Physiologie (Bucarest)
|January 1, 1988
Abstract:
The effects of acute ethanol intoxication in different rat organs were studied with 32P. Since 32P incorporation in all compounds of cell membrane formation faithfully illustrate their structural and functional integrity, levels of 32P labelled phospholipids, from different organs were investigated in acute experiments. Researches were carried out on male rats, by administering doses of 3.5 and 5.8 g/kg body wt., and killing them at 2, 4, 6, 24, 48, and 72 hours. The response of the liver, brain, kidneys and spleen depends on the administered dose and varies with time.