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Updated: Jan 21, 2026

Generation of RNA/DNA Hybrids in Genomic DNA by Transformation using RNA-containing Oligonucleotides
Published on: November 24, 2010
Synthetic DNA and RNA Programming
Patrick O'Donoghue1,2, Ilka U Heinemann3
1Department of Biochemistry, The University of Western Ontario, London, ON N6A 5C1, Canada. patrick.odonoghue@uwo.ca.
Abstract:
Synthetic biology is a broad and emerging discipline that capitalizes on recent advances in molecular biology, genetics, protein and RNA engineering as well as omics technologies. Together these technologies have transformed our ability to reveal the biology of the cell and the molecular basis of disease. This Special Issue on "Synthetic RNA and DNA Programming" features original research articles and reviews, highlighting novel aspects of basic molecular biology and the molecular mechanisms of disease that were uncovered by the application and development of novel synthetic biology-driven approaches.
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