Related Experiment Video
Updated: Jan 21, 2026

Author Spotlight: Developing Cost-Effective and Durable Ultrasound-Guided 3D-Printed Nerve Block Trainers
Published on: February 9, 2024
Ultrasound-Guided Block of the Axillary Nerve: A Prospective, Randomized, Single-Blind Study Comparing Interfascial
Eung Don Kim1, Jung Won Baek2, Ji Seob Kim2
1Department of Anesthesiology and Pain Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Background:
The ultrasound-guided block of the axillary nerve may be complicated in cases in which the posterior circumflex humeral artery (PCHA) follows an abnormal course.
Objectives:
To develop a new technique that does not rely on direct visualization of the PCHA or the axillary nerve, and to compare interfascial injection and conventional perivascular injection for a block of the axillary nerve.
Study Design:
A prospective randomized study.
Setting:
An interventional pain-management practice in a university hospital.
Methods:
A total of 56 patients received ultrasound-guided block of the axillary nerve with either interfascial injection (IF Group) or perivascular injection with nerve stimulation (PV Group). The primary outcome was procedure duration, defined as the time interval from when the transducer contacted the skin to when the needle was removed from the skin.
Results:
The mean procedure time was significantly shorter in the IF Group than in the PV Group (64 seconds [SD 28.3] vs. 135 seconds [50.3], difference of -71.4 seconds; 95% confidence interval, -93.2 to -49.5) (P < 0.001). There were no differences in secondary outcomes, including the quality of blocks, between the 2 groups.
Limitations:
The practitioner was not blinded to the group to which the patients belonged.
Conclusions:
Ultrasound-guided block of the axillary nerve with interfascial injection can be performed without placing the needle near the PCHA.
Key Words:
Block of axillary nerve, ultrasound-guided block, posterior circumflex humeral artery, interfascial injection.
Related Concept Videos
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
Blind Procedures
Blinding
Random Error
Random Variables
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
Randomized Experiments
Simple randomization
Simple...

