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Updated: Jan 21, 2026

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy
Published on: May 18, 2011
Recent developments in spontaneous Raman imaging of living biological cells
Bianca Durrant1, Matthew Trappett1, Dustin Shipp1
1Department of Physics, Utah Valley University, 800 West University Parkway, Orem, UT 84058, United States.
Abstract:
Raman spectroscopy is a non-invasive optical technique for measuring chemical information from samples including biological cells. With its high sensitivity and compatibility with in vitro samples, Raman spectroscopy is increasing in popularity as a tool for acquiring chemical images of cellular samples in fields including parasitology, pharmacology, and oncology. This review describes emerging technologies that are improving the speed, resolution, and impact of Raman imaging techniques. Topics include novel instrumentation for data acquisition and improvements on techniques for displaying hyperspectral data as images.
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