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Updated: Jan 21, 2026

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
Published on: July 28, 2018
Negative-pressure pulmonary edema after laparoscopic appendectomy
1At the time this article was written, Wei Chao Chang practiced in the Department of Surgery at MedStar Good Samaritan Hospital in Baltimore, Md. He now practices in the Department of Surgery at Greater Baltimore Medical Center. The author has disclosed no potential conflicts of interest, financial or otherwise.
Abstract:
Negative-pressure pulmonary edema (NPPE) is acute-onset bilateral pulmonary interstitial edema. This condition can be caused by significant negative intrathoracic pressure generated by large inspiratory effort against acute upper airway obstruction. Postoperative NPPE is rare but potentially life-threatening if not recognized and treated promptly. This article describes a patient who developed postoperative NPPE following a laparoscopic appendectomy.
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