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Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients
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Metabolic implications of low muscle mass in the pediatric population: a critical review

Camila E Orsso1, Jenneffer R B Tibaes2, Daniela A Rubin3

  • 1Department of Agricultural, Food and Nutritional Science, 4-002 Li Ka Shing Centre for Health and Research, University of Alberta, Edmonton, AB T6G 2E1, Canada.

Metabolism: Clinical and Experimental
|July 27, 2019
PubMed

Insights

Low muscle mass in children may increase metabolic risks, but evidence is conflicting. More research is needed to understand the link between pediatric body composition and metabolic health.

Area of Science:

  • Pediatric Endocrinology
  • Metabolic Health
  • Body Composition Analysis

Background:

  • Skeletal muscle plays a crucial role in glucose and lipid metabolism.
  • Low muscle mass is linked to metabolic disorders in adults, but its role in children is less understood.

Purpose of the Study:

  • To review the association between low muscle mass and metabolic dysregulation in the pediatric population.
  • To evaluate if body composition phenotypes predict metabolic health in children and adolescents.

Main Methods:

  • A critical evaluation of fifteen original articles was performed.
  • Studies examined the relationship between muscle mass measures and metabolic risk factors in pediatric populations.

Main Results:

  • Evidence suggests low muscle mass may be a risk factor for metabolic health in children and adolescents.
  • Conflicting associations were reported, potentially due to variations in methodology and assessment techniques.

Conclusions:

  • The current evidence is inconsistent regarding low muscle mass as a risk factor for pediatric metabolic health.
  • Further research with standardized, precise methods is required to clarify these associations and control for confounders.

Keywords:
Body compositionChildrenMetabolic dysregulationMuscle mass

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