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Clinical Characteristics in Patients with Rheumatoid Arthritis: Differences between Genders.

M Intriago1, G Maldonado1, J Cárdenas1

  • 1Universidad Espíritu Santo, Km. 2.5 Vía la Puntilla Samborondón, Ecuador.

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Summary
This summary is machine-generated.

Women with rheumatoid arthritis (RA) experience more severe symptoms and disease activity than men. This study highlights significant gender-based differences in RA presentation and impact.

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Area of Science:

  • Rheumatology
  • Clinical Medicine
  • Gender Studies in Health

Background:

  • Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting joints.
  • Understanding gender-specific differences in RA is crucial for tailored treatment strategies.

Purpose of the Study:

  • To compare the clinical characteristics and disease activity between male and female patients with RA.
  • To identify gender-based disparities in RA presentation and impact.

Main Methods:

  • A cross-sectional study involving 50 men and 50 women diagnosed with RA.
  • Data collection included clinical manifestations, comorbidities, treatment, and disease activity assessments (DAS-28, HAQ-DI, ESR).

Main Results:

  • Women reported higher rates of fatigue, loss of appetite, and weight loss.
  • Women exhibited significantly higher disease activity scores (DAS-28), functional disability (HAQ-DI), and inflammatory markers (ESR).
  • Men showed higher rates of tobacco and alcohol consumption.

Conclusions:

  • Female RA patients present with a more aggressive disease course characterized by greater disease activity and disability.
  • Findings align with existing literature indicating sex-based differences in RA severity and progression.