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Moffett's Solution Causes Significantly Greater Postoperative Throat Pain Compared to Cophenylcaine in Sinonasal
Dominic Ku1, Kartik Vasan1, Eugene Wong1
1Department of Otolaryngology, Westmead Hospital, Sydney, New South Wales, Australia.
Aim:
Preoperative decongestion with Moffett's solution is routine practice in sinonasal procedures providing an ideal operative field. Anecdotally, it is related to postoperative throat pain, yet a quantitative relationship has not been established. We compare the incidence and severity of postoperative throat pain after application of Moffett's solution against Cophenylcaine decongestion.
Methodology:
A total of thirty patients from two consultants were recruited. The intervention arm (twenty) was decongested with Moffett's solution and the control arm (ten) with Cophenylcaine. The primary outcome was self-reported postoperative throat pain as measured by visual analogue scale (VAS) at 2 hours, 4 hours, 6 hours, and next morning.
Results:
There was a significantly higher VAS for throat pain in patients decongested with Moffett's solution in the early postoperative period (2 hours p=0.03, 4 hours p=0.04).
Conclusion:
Moffett's solution is associated with a greater severity of transient postoperative throat pain compared to topical Cophenylcaine. We recommend further studies to identify means to minimise this side effect.
Clinical Trial Registration:
This paper has been registered with the Australian and New Zealand Clinical Trials Registry under the registration number: ACTRN12619000772145.
Insights
Moffett's solution, used for preoperative decongestion, causes more transient postoperative throat pain than Cophenylcaine. Further research is recommended to minimize this common side effect in sinonasal procedures.
Area of Science:
- Otolaryngology
- Surgical Innovation
- Pain Management
Background:
- Preoperative sinonasal decongestion is standard practice for optimizing surgical fields.
- Moffett's solution is commonly used, but its association with postoperative throat pain is anecdotal.
- Quantitative data on the incidence and severity of throat pain following Moffett's solution use is lacking.
Purpose of the Study:
- To quantitatively compare the incidence and severity of postoperative throat pain.
- To evaluate Moffett's solution against Cophenylcaine for sinonasal decongestion.
Main Methods:
- A comparative study involving 30 patients undergoing sinonasal procedures.
- Twenty patients received Moffett's solution (intervention), and ten received Cophenylcaine (control).
- Postoperative throat pain was measured using the Visual Analogue Scale (VAS) at set intervals.
Main Results:
- Patients receiving Moffett's solution reported significantly higher VAS scores for throat pain.
- This difference was notable in the early postoperative period (2 and 4 hours post-procedure).
Conclusions:
- Moffett's solution is associated with increased transient postoperative throat pain compared to Cophenylcaine.
- Further investigation is warranted to develop strategies for mitigating this adverse effect.