Related Experiment Video
Updated: Jan 21, 2026

Bedside Ultrasound for Guiding Fluid Removal in Patients with Pulmonary Edema: The Reverse-FALLS Protocol
Published on: July 28, 2018
High-flow oxygen therapy for treating re-expansion pulmonary edema
Sang Kwon Lee1, Bong Soo Son1, Joohyung Son1
1Department of Thoracic and Cardiovascular Surgery, Pusan National University Yangsan Hospital, Medical Research Institute of Pusan National University, Yangsan, South Korea.
Re-expansion pulmonary edema (REPE) is a dangerous complication after lung re-expansion. High-flow nasal cannula therapy successfully treated severe REPE, offering a safe alternative to mechanical ventilation.
Area of Science:
- Pulmonology
- Critical Care Medicine
Background:
- Re-expansion pulmonary edema (REPE) is a rare but life-threatening complication following rapid re-expansion of a collapsed lung.
- Mechanical ventilation, often used for respiratory failure in REPE, can exacerbate ventilation-perfusion mismatch and increase mortality risk.
Observation:
- Spontaneous breathing is crucial for managing REPE to avoid worsening ventilation-perfusion mismatch.
- High-flow nasal cannula (HFNC) therapy provides high oxygen concentrations while supporting spontaneous breathing, emerging as a potential alternative to mechanical ventilation.
Findings:
- This study successfully treated a patient with severe REPE using HFNC as a primary treatment modality.
- HFNC effectively managed respiratory distress in REPE without the need for mechanical ventilation.
Implications:
- HFNC represents a promising, less invasive therapeutic option for managing REPE.
- This approach may improve patient outcomes by avoiding the complications associated with mechanical ventilation in REPE cases.
Related Concept Videos
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue,...
Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy
Gene Therapy
Heat and Free Expansion
Thermal Expansion
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...

