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Epidermolysis bullosa pruriginosa: A rare entity which responded well to thalidomide
Seema Rani1, Aastha Gupta1, Minakshi Bhardwaj2
1Department of Dermatology, Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Abstract:
Epidermolysis bullosa pruriginosa is an unusual clinical variant of dystrophic epidermolysis bullosa characterized by sublamina densa blistering and intense pruritus leading to hypertrophic lichenoid nodules, plaques, milia, and variable presence of albopapuloid lesions. Most cases are sporadic but a few cases have autosomal dominant or recessive inheritance. Treatment has been quite disappointing and failed to produce satisfactory or sustained results. We report a case of 39-years-old male with epidermolysis bullosa pruriginosa and its response to thalidomide.
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