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'Entero-insular axis' and surgical trauma.
Scandinavian Journal of Gastroenterology
|June 1, 1988
Summary
Enteral glucose administration is feasible and superior to parenteral routes for postoperative energy supply. Postoperative glucose and insulin levels indicate a better response with enteral feeding, even early after abdominal surgery.
Area of Science:
- Metabolism
- Surgical Nutrition
- Endocrinology
Background:
- Optimal postoperative energy supply is crucial for patient recovery.
- Understanding glucose and insulin dynamics post-surgery is key to improving nutritional strategies.
Purpose of the Study:
- To compare the efficacy of enteral versus parenteral glucose administration for postoperative energy supply.
- To evaluate glucose and insulin responses to different glucose loads via enteral and parenteral routes.
Main Methods:
- Three different glucose loads (5 g, 15 g, 40 g) were administered.
- Glucose and insulin concentrations were measured pre- and post-operatively.
- Both enteral and parenteral routes of administration were studied.
Main Results:
- Glucose and insulin concentrations were dose-dependent for both administration routes.
- Postoperative insulin concentrations and the 'insulinogenic index' were significantly higher than preoperative levels.
- The 'insulinogenic index' was 3 to 10 times higher with enteral glucose compared to parenteral administration.
Conclusions:
- Enteral glucose administration is a viable and effective method for early postoperative energy supply.
- The enteral route appears superior to the parenteral route for glucose delivery in the early postoperative period.
- Findings support the use of enteral nutrition for optimizing surgical recovery.