Related Experiment Video
Updated: Jan 21, 2026

Evaluating the Function of the Foot Core System in the Elderly
Published on: March 11, 2022
Assessment of Functionality in Elderly Patients When Determining Appropriate Treatment for Nonmelanoma Skin Cancers
Michael A Renzi1, Matthew Belcher2, Bruce Brod3
1Division of Dermatology, Cooper Medical School of Rowan University, Camden, New Jersey.
Background:
The treatment of nonmelanoma skin cancer (NMSC) in the elderly population is a source of significant debate. Mohs micrographic surgery (MMS) is a highly effective treatment option yet not every patient with a cutaneous malignancy that meets appropriate use criteria (AUC) should be treated with surgery.
Objective:
The purpose of this study was to use the Karnofsky Performance Status (KPS) scale to categorize the functional status of patients aged 75 years and older who required treatment of NMSC. The authors wanted to see whether functionality played a role on the treatment selection.
Methods:
Patients aged 75 years and older presenting for biopsy of a suspected NMSC that met AUC for MMS were included in the study. Trained medical assistants used the KPS scale to assess patient functionality. Treatment modality was recorded once the biopsy confirmed the NMSC.
Results:
A cohort of 203 subjects met inclusion criteria for the study. There was a statistically significant difference in utilization of surgical treatments between high and low functionality patients (p = .03).
Conclusion:
Dermatologists consider patient functionality when selecting a treatment for NMSC and use less invasive modalities for patients with poor functional status, even when the tumor meets AUC.
Insights
Patient functionality impacts nonmelanoma skin cancer (NMSC) treatment selection in elderly patients. Dermatologists opt for less invasive methods for those with lower functional status, even if surgery is indicated.
Area of Science:
- Dermatology
- Geriatric Medicine
- Surgical Oncology
Background:
- Treatment of nonmelanoma skin cancer (NMSC) in the elderly presents challenges.
- Mohs micrographic surgery (MMS) is effective but not universally applicable.
- Appropriate use criteria (AUC) guide surgical decisions.
Purpose of the Study:
- To assess the role of patient functionality in NMSC treatment selection for elderly patients.
- To utilize the Karnofsky Performance Status (KPS) scale for functional assessment.
- To determine if functional status influences the choice of NMSC treatment modality.
Main Methods:
- Included patients aged 75+ with NMSC meeting AUC for MMS.
- Assessed patient functionality using the KPS scale.
- Recorded NMSC treatment modality post-biopsy confirmation.
Main Results:
- A cohort of 203 elderly patients was analyzed.
- A statistically significant difference in surgical treatment utilization was observed between high and low functionality groups (p = .03).
Conclusions:
- Patient functionality is a key consideration in NMSC treatment planning for older adults.
- Dermatologists adjust treatment strategies based on patient functional status.
- Less invasive treatments are favored for elderly patients with poorer functional status, irrespective of AUC.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Sensory Functions of the Skin
There are two main categories of receptors on the skin: capsulated and non-capsulated. The non-capsulated ones are mainly the pain receptors. The capsulated ones can be further categorized based on the...
Treatment Resistant Cancers
Assessment of Airway, Skin Color, and Use of Accessory Muscles
Introduction
The initial evaluation of a patient's respiratory system...
Nursing Process for Patient and Caregiver Teaching I: Assessment and Diagnosis
It is critical to determine the patient's learning needs during the assessment. Determination of learning needs compounds data...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

