Related Experiment Video
Updated: Jan 21, 2026

Production and Detection of Reactive Oxygen Species ROS in Cancers
Published on: November 21, 2011
A New control structure for tert-amyl methyl ether production using reactive distillation
Shahin Kharaji1, Jafar Sadeghi1, Farhad Shahraki1
1Center for Process Integration and Control (CPIC), Department of Chemical Engineering, University of Sistan and Baluchestan, Zahedan 98164, Iran.
Abstract:
The aim of this paper is to introduce new control structures in both centralized and decentralized scheme for tert-amyl methyl ether (TAME) production unit using reactive distillation which developed as a benchmark by Luyben (2005). Steady state and dynamic simulation was performed based on the case study data using Aspen® simulator. Dynamic simulation shows that control performance of the plant has oscillatory behavior using conventional PI controllers. Hence, a proper modification on the process flow sheet was carried out in order to remove oscillatory behavior of the process. Although, the new structure has better dynamic performance than the previous one using PI controller, it is not capable of eliminating the oscillations completely. Non-minimal state space with proportional integral plus controller (NMSS-PIP) controller was applied to dynamic model of the modified process. In this way, the system identification was carried out using refined instrumental variable (RIV) method and state matrices was obtained as left matrix fraction description (LMFD). The control performance of the PI and PIP controller for the modified structure revealed that the NMSS-PIP, completely eliminates the process oscillations while it has smoother responses with better settling time than the PI configuration. Furthermore, comparison of the ITAE criterion between main case and modified process indicates that the ITAE for PI and PIP control decreased by about 20% and 88%, respectively.
Related Concept Videos
Structure and Nomenclature of Ethers
Ethers are organic compounds with an ether functional group which is characterized by an oxygen atom connected to two — identical or different — alkyl, aryl, or vinyl groups. The C–O–C linkage in dimethyl ether — the simplest ether — has an approximately tetrahedral bond angle of 110.3 degrees. The oxygen atom is sp3- hybridized, with the C–O distance being about 140 pm.
Classification of Ethers
Based on their attached substituent...
Structural Steel Products
Once shaped, the steel's final form emerges as a continuous length, which is then segmented by a hot saw into manageable pieces. These segments...
Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
Crown Ethers
Physical Properties of Ethers
An ether molecule has a net dipole moment due to the polarity of C–O bonds. Subsequently, boiling points of ethers are lower than those of alcohols of comparable molecular weight and slightly higher than those of hydrocarbons of comparable molecular weight (Table 1).
Ethers can act as hydrogen bond acceptors, making them more water-soluble than hydrocarbons, but since ethers cannot act as hydrogen bond donors, they are much less soluble in water than alcohols. Ethers are considered...
Distillation: Vapor–Liquid Equilibria

