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Updated: Jan 21, 2026

Corticospinal Excitability Modulation During Action Observation
Published on: December 31, 2013
Is it necessary to show virtual limbs in action observation neurorehabilitation systems?
Cristián Modroño1, Sergi Bermúdez2,3, Mónica Cameirão2,3
1Departamento de Ciencias Médicas Básicas, Universidad de La Laguna, Tenerife, España.
Introduction:
Action observation neurorehabilitation systems are usually based on the observation of a virtual limb performing different kinds of actions. In this way, the activity in the frontoparietal Mirror Neuron System is enhanced, which can be helpful to rehabilitate stroke patients. However, the presence of limbs in such systems might not be necessary to produce mirror activity, for example, frontoparietal mirror activity can be produced just by the observation of virtual tool movements. The objective of this work was to explore to what point the presence of a virtual limb impacts the Mirror Neuron System activity in neurorehabilitation systems.
Methods:
The study was conducted by using an action observation neurorehabilitation task during a functional magnetic resonance imaging (fMRI) experiment with healthy volunteers and comparing two action observation conditions that: 1 - included or 2 - did not include a virtual limb.
Results:
It was found that activity in the Mirror Neuron System was similar during both conditions (i.e. virtual limb present or absent).
Conclusions:
These results open up the possibility of using new tasks that do not include virtual limbs in action observation neurorehabilitation environments, which can give more freedom to develop such systems.
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