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Updated: Jan 21, 2026

Preparation and Reactivity of Gasless Nanostructured Energetic Materials
Published on: April 2, 2015
Impact of Stereo- and Regiochemistry on Energetic Materials
Lisa M Barton1, Jacob T Edwards1, Eric C Johnson2
1Department of Chemistry , Scripps Research Institute , 10550 North Torrey Pines Road , La Jolla , California 92037 , United States.
Abstract:
The synthesis, physical properties, and calculated performances of six stereo- and regioisomeric cyclobutane nitric ester materials are described. While the calculated performances of these isomers, as expected, were similar, their physical properties were found to be extremely different. By alteration of the stereo- and regiochemistry, complete tunability in the form of low- or high-melting solids, stand-alone melt-castable explosives, melt-castable explosive eutectic compounds, and liquid propellant materials was obtained. This demonstrates that theoretical calculations should not be the main factor in driving the design of new materials and that stereo- and regiochemistry matter in the design of compounds of potential relevance to energetic formulators.
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