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Updated: Jan 21, 2026

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Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
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Airway Obstruction Risk in Unique Infant Cleft Phenotype: PSIO Protocol Modification Recommendations
Aaron M Foglio1, Jonathan Y Lee2, Sanjay Naran1,3
1Department of Plastic Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, USA.
Summary
Infants with a specific unilateral cleft lip and palate may experience nasal airway obstruction, worsened by presurgical infant orthopedic (PSIO) devices. Lip-nose adhesion (LNA) effectively relieved obstruction in a case study.
Area of Science:
- Craniofacial Surgery
- Pediatric Otolaryngology
- Cleft Lip and Palate Research
Background:
- Unilateral cleft lip and palate can cause unique nasal airway obstruction.
- Presurgical infant orthopedic (PSIO) therapy and lip taping may exacerbate breathing difficulties in these infants.
- Specific alveolar segment positioning contributes to bilateral nasal obstruction.
Purpose of the Study:
- To describe a unique unilateral cleft phenotype causing nasal airway obstruction.
- To evaluate the efficacy of lip-nose adhesion (LNA) in relieving obstruction.
- To discuss treatment alternatives for infants with this specific cleft anatomy.
Main Methods:
- Case presentation of four patients with a distinct unilateral cleft phenotype.
- Description of bilateral nasal airway obstruction mechanisms.
- Surgical technique and outcomes of lip-nose adhesion (LNA).
Main Results:
- Patients presented with anterior greater alveolar segment projection and posterior lesser segment collapse.
- Bilateral nasal airway obstruction was observed due to cleft ala drape and caudal septum displacement.
- Lip-nose adhesion (LNA) provided immediate relief of airway obstruction.
Conclusions:
- Lip-nose adhesion (LNA) effectively addresses nasal airway obstruction in this specific cleft phenotype.
- Careful consideration of PSIO appliance modification versus LNA is crucial.
- Multidisciplinary consultation involving surgeons, PSIO providers, and caretakers is recommended.
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