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Related Experiment Video

Updated: Jan 21, 2026

A New Murine Model of Endovascular Aortic Aneurysm Repair
08:51

A New Murine Model of Endovascular Aortic Aneurysm Repair

Published on: July 7, 2013

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Aortic Bifurcation Saddle Thrombus.

Casey Arnold1, Carmen J Martinez Martinez1

  • 1Emergency Medicine, Advent Health Florida Hospital, Orlando, USA.

Cureus
|August 1, 2019
PubMed
Summary
This summary is machine-generated.

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IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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Aortic Regurgitation III: Medical Management01:25

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Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
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Aortic Regurgitation IV: Nursing Management01:17

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A nurse managing a patient with aortic regurgitation begins with a comprehensive assessment, including a review of the patient's medical history, family history, and lifestyle factors. During the cardiac examination, the nurse listens for heart sounds and checks for signs of valve abnormalities. The nurse also observes for symptoms such as dyspnea, orthopnea, and paroxysmal nocturnal dyspnea and assesses the patient's endurance and daily activity tolerance.Based on the findings, the nurse...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

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Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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Anatomy of the Heart01:27

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The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
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A rare aortic saddle thrombus caused acute aortic occlusion in a patient presenting with chest pain. Prompt reevaluation in the emergency department is crucial for diagnosing acute aortic pathology and preventing fatal outcomes.

Area of Science:

  • Cardiology
  • Vascular Surgery
  • Emergency Medicine

Background:

  • Acute aortic pathology requires high clinical suspicion and frequent reevaluation for accurate diagnosis.
  • Delayed diagnosis of aortic conditions can lead to severe morbidity and mortality.

Observation:

  • A 59-year-old male presented to the emergency department with chest pain.
  • Initial assessment did not reveal the underlying cause of his symptoms.

Findings:

  • A rare aortic bifurcation saddle thrombus causing acute aortic occlusion was diagnosed upon thorough reevaluation.
  • This diagnosis highlights the importance of reassessing patients with potential acute aortic syndromes, especially when diagnostic clues are present.

Implications:

Keywords:
acute aortic occlusionacute aortoiliac occlusionaortic thrombuscardiac thrombusintraventricular thrombussaddle thrombus

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  • Early and repeated evaluation is critical for identifying potentially fatal aortic conditions.
  • Failure to diagnose acute aortic occlusion can result in death or the need for lifelong hemodialysis.