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Updated: Jan 21, 2026

Randomized, Triple-Blind, and Parallel-Controlled Trial of Transcranial Direct Current Stimulation for Cognitive Rehabilitation after Stroke
Published on: June 6, 2025
Regaining Confidence after Stroke (RCAS): a feasibility randomised controlled trial (RCT).
Jane C Horne1, Kate E Hooban1, Nadina B Lincoln1
1University of Nottingham, School of Medicine, Division of Rehabilitation and Ageing, B floor-Rm98, QMC Campus, Nottingham, NG7 2UH UK.
This study found that the Regaining Confidence after Stroke (RCAS) course is a feasible intervention for stroke survivors. The randomized trial demonstrated the potential effectiveness of the RCAS course compared to usual care.
Area of Science:
- Rehabilitation Medicine
- Clinical Psychology
- Health Services Research
Background:
- The Regaining Confidence after Stroke (RCAS) course aims to aid post-rehabilitation adjustment for stroke survivors.
- Evaluating the feasibility of a randomized trial comparing RCAS to usual care was the primary objective.
Purpose of the Study:
- To assess the feasibility of a randomized trial for the RCAS course.
- To evaluate screening, recruitment, consent, retention, outcome measure acceptability, and intervention fidelity and acceptability.
Main Methods:
- 47 stroke participants were randomized to either the RCAS course or usual care.
- The RCAS course involved 11 weekly sessions; fidelity was assessed via checklist, and acceptability through interviews.
- Outcomes were measured at 3 and 6 months post-randomization.
Main Results:
- Participant recruitment and retention rates supported trial feasibility.
- Intervention fidelity indicated alignment with the manual, though therapist training may be needed.
- The RCAS course was found to be acceptable and beneficial, with good attendance rates.
Conclusions:
- The study supports the feasibility of conducting a randomized trial to assess the effectiveness of the RCAS course.
- Further research can proceed to evaluate the RCAS course's impact on stroke survivor adjustment.
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