Related Experiment Video

Updated: Jan 21, 2026

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
05:42

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation

Published on: October 25, 2024

1.6K

Differences in the Selvester QRS score after primary PCI strategy and conservative treatment for STEMI patients with

Egle Kalinauskiene1, Dalia Gerviene1, Ljuba Bacharova2,3

  • 1Department of Internal Medicine, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
|August 2, 2019
PubMed

Insights

Conservative treatment may be a viable option for ST-elevation myocardial infarction (STEMI) patients presenting with a negative T wave, showing reduced infarct size without significant changes in the primary PCI group. Higher mortality in the non-PCI group was linked to age and comorbidities.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Emergency Medicine

Background:

  • Current ST-elevation myocardial infarction (STEMI) guidelines prioritize PCI for ST-segment deviations and symptom onset time.
  • A negative T wave on admission ECG in STEMI may indicate prolonged ischemia or spontaneous reperfusion, questioning the need for urgent intervention.
  • This study investigates infarct size and mortality in STEMI patients with negative T waves, comparing primary percutaneous coronary intervention (PCI) with conservative management.

Purpose of the Study:

  • To evaluate the impact of primary PCI versus conservative treatment on infarct size in STEMI patients with a negative T wave.
  • To compare in-hospital mortality rates between primary PCI and conservative treatment strategies in this patient cohort.
  • To determine if a negative T wave on presenting ECG influences the optimal treatment strategy for STEMI.

Main Methods:

  • Retrospective analysis of 116 STEMI patients with a negative T wave on presenting ECG.
  • Patients were divided into two groups: primary PCI (n=68) and conservative treatment (n=48).
  • Infarct size was assessed using the Selvester score, and in-hospital mortality was recorded.

Main Results:

  • A statistically significant reduction in infarct size (Selvester score) was observed in the conservative treatment group (1.48; 95% CI 0.694-2.27).
  • No significant change in infarct size was found in the primary PCI group (-0.07; 95% CI -0.546-0.686).
  • In-hospital mortality was higher in the conservative group (10.4%) compared to the PCI group (2.9%), though numbers were small and potentially confounded by age and comorbidities.

Conclusions:

  • Conservative management led to a reduction in infarct size in STEMI patients with negative T waves, unlike primary PCI.
  • Higher mortality in the conservative group may be attributed to older age and comorbidities.
  • Conservative treatment strategy could be a potential option for selected STEMI patients presenting with a negative T wave.
Abstract

Keywords:
ST-segment elevation myocardial infarctionSelvester QRS scoreconservative treatmentin-hospital mortalityprimary PCI strategy

More Related Videos

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index06:55

Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

Published on: January 8, 2020

15.1K
Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

806

Related Concept Videos

Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
741
What is Conservation Biology?01:57

What is Conservation Biology?

Conservation biology is a scientific field that focuses on the preservation of biodiversity in order to protect ecosystems while meeting the needs of the human population. Humans require properly functioning ecosystems to maintain our supply of natural resources, including food, medicines, and building materials.
24.0K
Conservation of Small Populations02:04

Conservation of Small Populations

Small population sizes put a species at extreme risk of extinction due to a lack of variation, and a consequent decrease in adaptability. This weakens the chances of survival under pressures such as climate change, competition from other species, or new diseases. Large populations are more likely to survive pressures such as these, as such populations are more likely to harbor individuals that have genetic variants that are adaptive under new stresses. Small populations are much less...
16.7K
Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally...
5.0K
The Wave Nature of Light02:12

The Wave Nature of Light

The nature of light has been a subject of inquiry since antiquity. In the seventeenth century, Isaac Newton performed experiments with lenses and prisms and was able to demonstrate that white light consists of the individual colors of the rainbow combined together. Newton explained his optics findings in terms of a "corpuscular" view of light, in which light was composed of streams of extremely tiny particles traveling at high speeds according to Newton's laws of motion.
60.9K
Introduction to z Scores01:06

Introduction to z Scores

A z score (or standardized value) is measured in units of the standard deviation. It tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
11.0K