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Caring Process in Hematopoietic Stem Cell Transplantation: A Grounded Theory Study.

Leila Sayadi1,2, Vahid Zamanzadeh3, Leila Valizadeh3

  • 1Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.

International Journal of Hematology-Oncology and Stem Cell Research
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PubMed
Summary

Caring for Hematopoietic Stem Cell Transplantation (HSCT) patients involves supporting them through life-or-death struggles. Nursing strategies focus on reducing mortality risk and bolstering patient spirit for successful transplantation outcomes.

Keywords:
CaringGrounded theoryHematopoietic stem cell transplantationSupporting

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Area of Science:

  • Nursing Care
  • Hematopoietic Stem Cell Transplantation
  • Qualitative Research

Background:

  • Caring is a central nursing concept, with varied delivery modes across diseases.
  • Hematopoietic Stem Cell Transplantation (HSCT) is a complex, last-resort intervention for life-threatening conditions.
  • Understanding the nuances of HSCT patient care is crucial.

Purpose of the Study:

  • To explore the multifaceted process of caring for patients undergoing HSCT.
  • To identify key challenges and successful strategies in HSCT nursing.
  • To provide insights for improving HSCT patient care protocols.

Main Methods:

  • Qualitative research employing grounded theory methodology.
  • Data collection through interviews and observations of healthcare professionals, patients, and families.
  • Analysis using the Corbin & Strauss (2008) method with 39 participants.

Main Results:

  • Four emergent categories: patient's life-or-death struggle, efforts to reduce mortality, reinforcing patient spirit, and care achievements.
  • The core variable identified was "supporting patients to go through the HSCT process successfully".
  • Care strategies focused on mitigating death risk and enhancing patient resilience.

Conclusions:

  • HSCT patients experience a "life-and-death limbo" during the care process.
  • Effective HSCT care necessitates reducing mortality risks and strengthening patient spirit.
  • Findings can inform nursing practice, educational programs, and policy development for HSCT care.