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Updated: Jan 21, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Evolvulins I and II, Resin Glycosides with a Trihydroxy Aglycone Unit from Evolvulus alsinoides
Bo-Yi Fan1, Yun Lu1, Min Yang1
1School of Pharmacy , Nantong University , 19 Qixiu Road , Nantong , Jiangsu Province 226001 , People's Republic of China.
Abstract:
Evolvulins I and II (1 and 2), representing a new class of resin glycosides with an unprecedented trihydroxy aglycone unit, 3S,11R,14R-trihydroxyhexadecanoic acid (4), were isolated from the whole plants of Evolvulus alsinoides. Their structures were thoroughly characterized by extensive spectroscopic analyses as well as chemical evidence. Compound 1 exhibited the most potent cytotoxic activity against MCF-7 cells, with an IC50 value of 3.12 μM.
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