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Related Concept Videos

Translation01:31

Translation

155.7K
Lesson: Translation
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of...
155.7K
Translation01:31

Translation

17.6K
Translation is the process of synthesizing proteins from the genetic information carried by messenger RNA (mRNA). Following transcription, it constitutes the final step in the expression of genes. This process is carried out by ribosomes, complexes of protein and specialized RNA molecules. Ribosomes, transfer RNA (tRNA), and other proteins produce a chain of amino acids—the polypeptide—as the end product of translation.
Translation Produces the Building Blocks of Life
Proteins are...
17.6K
Initiation of Translation02:33

Initiation of Translation

38.4K
Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
38.4K
Termination of Translation01:44

Termination of Translation

27.5K
The large ribosomal subunit has several important structures essential to translation. These include the peptidyl transferase center (PTC) - which is the site where the peptide bond is formed - and a large, internal, water-filled tube through which the nascent polypeptide moves. This latter structure is called the Peptide Exit Tunnel, and it begins at the PTC and spans the body of the large ribosomal subunit. During translation, as the nascent polypeptide chain is synthesized, it passes through...
27.5K
Termination of Translation01:44

Termination of Translation

6.6K
6.6K
Improving Translational Accuracy02:07

Improving Translational Accuracy

14.1K
Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
14.1K

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Still Lost in Translation.

Molly A Barlow1, Andrea Villegas1, David J Cox1

  • 1Molly A. Barlow and Andrea Villegas, University of Florida; and David J. Cox, Johns Hopkins University School of Medicine.

Intellectual and Developmental Disabilities
|August 3, 2019
PubMed
Summary
This summary is machine-generated.

Interdisciplinary dialogue advances professional fields by avoiding false dichotomies and generalizations. Focusing on shared values, like improving quality of life, helps overcome these barriers for better collaboration.

Keywords:
applied behavior analysisbehaviorisminterdisciplinary communication

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Area of Science:

  • Interdisciplinary studies
  • Professional development
  • Disability Studies in Education

Background:

  • Interdisciplinary dialogue is crucial for professional advancement.
  • Barriers such as false dichotomies and faulty generalizations can impede progress.
  • Existing frameworks may present challenges in dialogue.

Purpose of the Study:

  • To identify and address barriers in interdisciplinary dialogue.
  • To promote productive conversations by avoiding specific false dichotomies.
  • To advance the understanding and practice within helping professions.

Main Methods:

  • Conceptual analysis of interdisciplinary dialogue barriers.
  • Identification of specific false dichotomies (medical model vs. DSE, normality approach).
  • Examination of faulty generalizations regarding practitioners.

Main Results:

  • False dichotomies regarding the medical model and Disability Studies in Education (DSE) hinder dialogue.
  • A "normality approach" for goal setting creates unnecessary divisions.
  • Generalizations about practitioners lead to misunderstandings.

Conclusions:

  • Avoiding specific false dichotomies and generalizations is key to productive interdisciplinary dialogue.
  • Centering conversations on the shared value of improving quality of life can overcome barriers.
  • This approach fosters collaboration and advancement in helping professions.