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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

229
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
229
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

191
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
191
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
234
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

199
Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
199
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

243
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
243
Interdisciplinary Care: The Health Care Team-I01:21

Interdisciplinary Care: The Health Care Team-I

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An interdisciplinary team includes many healthcare professionals working together and utilizing their skills, knowledge, and expertise to provide holistic and quality patient care.
Physicians
The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution...
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Kinematics and Ground Reaction Force Determination: A Demonstration Quantifying Locomotor Abilities of Young Adult, Middle-aged, and Geriatric Rats
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Geriatric Palliative Care.

Andy Lazris1

  • 1Personal Physician Care, 6334 Cedar Lane, Columbia, MD 21044, USA.

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|August 4, 2019
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Summary
This summary is machine-generated.

Aggressive medical treatments may not always benefit older adults. A palliative care approach can improve quality of life and longevity, focusing on frailty and specific conditions.

Keywords:
DementiaFAST scaleFrailtyGeriatric palliative careGeriatricsParkinson diseasePolypharmacySlow medicine

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Area of Science:

  • Geriatric Medicine
  • Palliative Care
  • Internal Medicine

Background:

  • Limited evidence supports aggressive treatment efficacy in the geriatric population.
  • Palliative care often aligns with patient preferences for improved quality of life and potential longevity.
  • The elderly face unique challenges regarding medical interventions and data scarcity.

Purpose of the Study:

  • To discuss the limitations of aggressive medical interventions in the elderly.
  • To highlight the benefits of palliative care in specific geriatric conditions.
  • To delineate the goals and central role of primary care in geriatric palliative approaches.

Main Methods:

  • Literature review and discussion of existing data on geriatric care.
  • Analysis of palliative care benefits across conditions like dementia, Parkinson's, and heart failure.
  • Exploration of frailty's role and specific palliative care objectives.

Main Results:

  • Palliative care can enhance quality of life and survival in older adults.
  • Key goals include reducing polypharmacy, preventing falls, and managing pain.
  • Primary care providers are central to implementing effective palliative strategies.

Conclusions:

  • Palliative care offers a valuable alternative to aggressive treatment in many geriatric cases.
  • Addressing frailty and specific conditions through palliation is crucial.
  • Integrated primary care is essential for successful geriatric palliative strategies.