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Updated: Jan 21, 2026

Multi-color Localization Microscopy of Single Membrane Proteins in Organelles of Live Mammalian Cells
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Toward Single-Organelle Lipidomics in Live Cells

Adrian Lita1, Andrey N Kuzmin2,3, Artem Pliss2,3

  • 1Neuro-Oncology Branch, Center for Cancer Research , National Cancer Institute, National Institutes of Health , Bethesda , Maryland 20892 , United States.

Analytical Chemistry
|August 6, 2019
PubMed
Summary

This study introduces a novel micro-Raman assay for single-organelle lipidomics, enabling high-resolution lipid profiling in live cells. This advancement overcomes limitations of conventional methods, allowing detailed analysis of lipid heterogeneity within subcellular structures.

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