Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vestibular adaptation to long-term stimuli.

O Bock, H von Koschitzky, W H Zangemeister

    Biological Cybernetics
    |June 1, 1979
    PubMed
    Summary

    This study investigated prolonged vestibular stimulation. Nystagmus response declined during rotational tests but reached a steady state during caloric tests, differing from current models.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Characterization of transient noise in Advanced LIGO relevant to gravitational wave signal GW150914.

    Classical and quantum gravity·2020
    Same author

    GW150914: First results from the search for binary black hole coalescence with Advanced LIGO.

    Physical review. D. (2016)·2020
    Same author

    Tests of General Relativity with GW170817.

    Physical review letters·2019
    Same author

    Constraining the p-Mode-g-Mode Tidal Instability with GW170817.

    Physical review letters·2019
    Same author

    Search for Subsolar-Mass Ultracompact Binaries in Advanced LIGO's First Observing Run.

    Physical review letters·2018
    Same author

    GW170817: Measurements of Neutron Star Radii and Equation of State.

    Physical review letters·2018

    Area of Science:

    • Vestibular system physiology
    • Neuroscience
    • Human physiology

    Background:

    • Understanding the vestibular system's response to prolonged stimulation is crucial for diagnosing balance disorders.
    • Current mathematical models predict a decline in nystagmus response during sustained vestibular tests.
    • Distinguishing between direct thermal effects and true vestibular responses is challenging in caloric testing.

    Purpose of the Study:

    • To develop and describe experimental procedures for prolonged vestibular stimulation.
    • To differentiate direct thermal effects from vestibular nerve responses during long-term caloric tests.
    • To compare the time course of nystagmus during prolonged rotational and caloric vestibular tests.

    Main Methods:

    • Enlarged stimulus duration in vestibular per-acceleratory tests.
    • Procedures to rule out direct thermal effects on the vestibular nerve during long-term calorizations.
    • Recording and analysis of nystagmus time course during prolonged rotational and caloric stimulations.

    Main Results:

    • Experimental procedures were established for prolonged vestibular stimulation.
    • Direct thermal effects were successfully ruled out in long-term caloric tests.
    • Nystagmus response showed a distinct decline during prolonged rotation, aligning with models.
    • Nystagmus in caloric tests reached a steady state, maintained for at least 15 minutes, diverging from model predictions.

    Conclusions:

    • The time course of nystagmus during prolonged vestibular stimulation differs significantly between rotational and caloric tests.
    • Current mathematical models may need revision to account for steady-state nystagmus observed in prolonged caloric tests.
    • The findings highlight the importance of considering stimulation modality when interpreting vestibular test results.

    Related Experiment Videos