Related Experiment Video
Updated: Jan 21, 2026

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
Published on: August 24, 2018
Influence of simulated gastric juice on surface characteristics of CAD-CAM monolithic materials
Marlon E M Cruz1, Rafaela Simões1, Samira B Martins2
1Graduate student, Araraquara Dental School, São Paulo State University (UNESP), Araraquara, Brazil.
Statement Of Problem:
How the surfaces of monolithic esthetic restorations behave in the presence of acidic substances is unclear.
Purpose:
The purpose of this in vitro study was to evaluate the effect of simulated gastric juice on roughness, morphology, microhardness, substance loss, and color change of computer-aided design and computer-aided manufacturing (CAD-CAM) monolithic materials.
Material And Methods:
Disks from Lava Ultimate, VITA ENAMIC, IPS e.max CAD, and VITA SUPRINITY were analyzed for roughness, morphology, and microhardness by using a confocal microscope, scanning electron microscope (SEM), and Vickers hardness tester. Substance loss was determined by weighing the specimens on an analytical balance, and color change (ΔE) was assessed by using a spectrophotometer based on the CIELab parameters. All analyses were carried out before and after acid exposure.
Results:
Acid exposure significantly decreased the roughness, having a very high effect size on this property. The material was highly decisive in determining the microhardness, presenting the following order: VITA SUPRINITY>IPS e.max CAD>VITA ENAMIC>Lava Ultimate. The mass was not significantly affected by the acidic challenge. No significant difference in ΔE was found between Lava Ultimate and VITA ENAMIC and between IPS e.max CAD and VITA SUPRINITY. Lava Ultimate showed a higher ΔE than IPS e.max CAD and VITA SUPRINITY, whereas VITA ENAMIC exhibited higher ΔE only when compared with VITA SUPRINITY. All materials presented ΔE<1.
Conclusions:
The simulated gastric juice significantly influenced the roughness of all the evaluated materials and promoted a color change classified as clinically undetectable in all materials.
Related Concept Videos
C4 Pathway and CAM
C4 Pathway
The C4 pathway is used by plants such as...
Pancreatic Juice and Secretion
When acidic chyme from the stomach enters the duodenum, it triggers the release of secretin, a hormone that prompts pancreatic juice secretion. After a fatty meal, cholecystokinin, another hormone, stimulates gallbladder contraction and enhances enzyme-rich...
Characteristics of Life
Gastric Motility
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
Gastric Emptying
Gastric Phase of Digestion
When food enters the stomach, it stretches the stomach walls and activates stretch receptors. This triggers local reflexes of the enteric nervous system, mediated through the myenteric plexus. These...

