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Updated: Jan 21, 2026

A Photonic System for Generating Unconditional Polarization-Entangled Photons Based on Multiple Quantum Interference
Published on: September 5, 2019
Modern Anesthetic Ethers Demonstrate Quantum Interactions with Entangled Photons
Ryan K Burdick1, Juan P Villabona-Monsalve1, George A Mashour2
1Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
General anesthetics like sevoflurane and isoflurane interact with entangled photons, suggesting quantum mechanisms may underlie anesthetic-induced unconsciousness. This study provides the first experimental evidence for such quantum interactions in anesthetics.
Area of Science:
- Quantum Physics
- Anesthesiology
- Physical Chemistry
Background:
- The mechanism of anesthetic-induced unconsciousness is not fully understood.
- Previous research noted links between general anesthesia and physical changes like electron spin.
- No empirical evidence has demonstrated functional quantum interactions of general anesthetics.
Purpose of the Study:
- To investigate the linear and non-linear optical properties of halogenated ethers.
- To determine if general anesthetics exhibit quantum interactions.
- To explore potential quantum mechanical underpinnings of anesthetic action.
Main Methods:
- Utilized UV-Vis spectroscopy and time-dependent density functional theory (TD-DFT) calculations.
- Employed classical and entangled two-photon spectroscopy.
- Studied sevoflurane (SEVO) and isoflurane (ISO), comparing them to diethyl ether.
Main Results:
- Sevoflurane and isoflurane interacted with 800 nm entangled photons.
- Neither SEVO nor ISO interacted with 800 nm classical photons.
- Nonhalogenated diethyl ether did not interact with entangled photons, unlike its halogenated counterparts.
Conclusions:
- This study provides the first experimental evidence that halogenated anesthetics can undergo quantum interaction mechanisms.
- The findings suggest a novel approach to understanding the physicochemical properties of anesthetics.
- Quantum interactions may play a role in the mechanism of anesthetic-induced unconsciousness.
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Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
The Quantum-Mechanical Model of an Atom
Structure and Nomenclature of Ethers
Ethers are organic compounds with an ether functional group which is characterized by an oxygen atom connected to two — identical or different — alkyl, aryl, or vinyl groups. The C–O–C linkage in dimethyl ether — the simplest ether — has an approximately tetrahedral bond angle of 110.3 degrees. The oxygen atom is sp3- hybridized, with the C–O distance being about 140 pm.
Classification of Ethers
Based on their attached substituent...
Crown Ethers
Modern Molecular Taxonomy

