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Treating infants with neonatal abstinence syndrome: an examination of three protocols
Morgan J Hartgrove1, Laurie L Meschke2, Terry L King3
1University of Tennessee, Knoxville, TN, 37996, USA.
Objective:
Describe the characteristics of infants with NAS and determine if treatment outcomes varied between three protocols.
Study Design:
Based on medical record data, infant treatment for NAS-related withdrawal reflected one of three protocols: (1) No rescue dose (n = 836, 52.7%): Prescriber ordered initiation and escalation doses and determined when infants were eligible for weaning, (2) Rescue dose (n = 233, 14.7%): No rescue dose with the addition of a prescriber-ordered rescue dose, (3) Rescue dose by order set (n = 516, 32.6%): Rescue dose with addition of nurse-assisted order of morphine during escalation.
Results:
The no rescue dose group had longer length of stay, days to wean, and inpatient days, and greater initial morphine dose than the two rescue dose groups (p < 0.001). Treatment outcomes between the two rescue dose protocols did not differ.
Conclusions:
The benefits related to rescue dosing further inform the development of a standardized NAS treatment protocol.
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