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Updated: Jan 21, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
Published on: April 21, 2023
Antimicrobial Activity of Biosynthesized Silver Nanoparticles Decorated Silica Nanoparticles
Sachin V Otari1, Sanjay K S Patel1, Vipin C Kalia1
1Department of Chemical Engineering, Konkuk University, Seoul, 05029 Republic of Korea.
Abstract:
The production of cheap and effective compound for medicinal application is a major challenge for scientific community. So, several biological materials have been explored for the possible application in material synthesis which are useful in biomedical uses. Here, biomolecules from green tea leaves were functionalized on the surface of silicon dioxide nanoparticles (GSiO2 NPs). Next, the decoration silver (Ag) NPs on the surface of the GSiO2 NPs was observed in very short time of incubation in aqueous AgNO3. Ultraviolet-visible spectroscopy confirmed the formation of Ag NPs and the high-resolution transmission and scanning electron microscopies confirmed the decoration of spherical Ag NPs of 10 to 15 nm size on the surface of GSiO2 NPs. The antimicrobial activity of the Ag-GSiO2 NPs was determined against Staphylococcus aureus and Escherichia coli. The Ag-GSiO2 NPs displayed sustainable antimicrobial activity compared to Ag ions. The results indicate the potential value of Ag-GSiO2 NPs in surgical material and food processing.
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