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Updated: Jan 21, 2026

Fixation of Ultrasound Transducers for Spinal Cord Neuromodulation in Mice
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What Is New in Neuromodulation?

Courtenay K Moore1, Jessica J Rueb2, Samir Derisavifard2

  • 1Glickman Urologic and Kidney Institute, Cleveland Clinic, 9500 Euclid Avenue, Q-10, Cleveland, OH, 44195, USA. MOOREC6@ccf.org.

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Summary
This summary is machine-generated.

Neuromodulation, including sacral and peripheral nerve stimulation, offers effective treatment for bladder and bowel dysfunction. Recent innovations include improved devices and home-based therapies for better patient outcomes.

Keywords:
LUTSNeuromodulationPTNSSacral neuromodulationTibial nerve stimulators

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Area of Science:

  • Urology
  • Neurology
  • Gastroenterology

Background:

  • Neuromodulation is a recognized treatment for refractory overactive bladder, urinary retention, and fecal incontinence.
  • Sacral and peripheral nerve stimulation modalities are established, safe, and effective.

Purpose of the Study:

  • To review recent literature on neuromodulation for pelvic disorders.
  • To highlight innovations, indications, and durability of sacral neuromodulation (SNM) and percutaneous tibial nerve stimulation (PTNS).

Main Methods:

  • Literature review of recent studies on SNM and PTNS.
  • Analysis of emerging technologies and novel applications.

Main Results:

  • SNM shows improved lead placement, lasting effects, and new applications for pelvic disorders.
  • Emerging technologies include smaller, MRI-compatible SNM devices.
  • PTNS may benefit specific patient groups, with new home-use implantable tibial nerve stimulators.

Conclusions:

  • Neuromodulation continues to evolve with technological advancements.
  • Innovations in SNM and PTNS offer expanded and more convenient treatment options for patients with pelvic floor dysfunction.