Related Experiment Video
Updated: Jan 21, 2026

In Vitro Differentiation of Mouse Granulocyte-macrophage-colony-stimulating Factor GM-CSF-producing T Helper THGM Cells
Published on: September 10, 2018
Large-vessel vasculitis associated with PEGylated granulocyte-colony stimulating factor
K Yukawa1, S Mokuda, Y Yoshida
1Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan.
Abstract:
A 71-year-old female with advanced endometrial cancer was treated with pegfilgrastim. She developed a fever within seven days, and contrast-enhanced computed tomography scans repeated within three days revealed rapidly progressive thickening of the aortic wall. When clinicians administer PEGylated granulocyte-colony stimulating factor (G-CSF) to cancer patients, drug-associated vasculitis should be suspected. This report discusses the manifestation of G-CSF-associated large-vessel vasculitis (LVV).
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