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Updated: Jan 21, 2026

Differential Scanning Calorimetry — A Method for Assessing the Thermal Stability and Conformation of Protein Antigen
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Stability and Conformational Resilience of Protein Disulfide Isomerase

Jessica Guyette1, Baggio Evangelista1, Suren A Tatulian2

  • 1Burnett School of Biomedical Sciences, College of Medicine , University of Central Florida , Orlando , Florida 32816 , United States.

Biochemistry
|August 9, 2019
PubMed
Summary

Protein disulfide isomerase (PDI) shows remarkable resilience to thermal denaturation, regaining significant structure and function. Its stability is influenced by redox status and specific structural domains, revealing key physical properties.

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