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Updated: Jan 21, 2026

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Use of pHluorin to Assess the Dynamics of Axon Guidance Receptors in Cell Culture and in the Chick Embryo
Published on: January 12, 2014
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Curve Modulation and Apex Migration Using Shilla Growth Guidance Rods for Early-onset Scoliosis at 5-Year Follow-up
John T Wilkinson1, Chad E Songy, David B Bumpass
1Arkansas Children's Hospital, University of Arkansas for Medical Sciences, Little Rock, AR.
Journal of Pediatric Orthopedics
|August 9, 2019
Summary
The Shilla procedure allows spinal growth, but the fused curve apex often shifts distally over time. This suggests distal adding-on rather than a crankshaft phenomenon, impacting patient selection.
Area of Science:
- Spinal surgery
- Pediatric orthopedics
- Skeletal deformity correction
Background:
- The Shilla procedure aims to correct early-onset spinal deformities while preserving spinal growth.
- It enables controlled axial skeletal growth, potentially reducing the need for frequent implant lengthening surgeries.
Purpose of the Study:
- To investigate trends in spinal curve evolution following Shilla implantation.
- To understand how these changes influence long-term outcomes in pediatric patients.
Main Methods:
- Retrospective review of 21 patients with Shilla implants for at least 5 years.
- Analysis of coronal curve characteristics (preoperative, postoperative, last follow-up).
- Assessment of apex migration, compensatory curve development, spinal growth, and need for definitive fusion.
Main Results:
- The curve apex migrated caudally in 57% of patients (mean 2.7 vertebral levels).
- Two patients developed new compensatory curves; all patients showed spinal growth (mean 45 mm).
- At skeletal maturity, 10 patients had definitive spinal fusion, and 3 had implant removal.
Conclusions:
- The fused primary curve apex shifts in 62% of patients, predominantly distally.
- Findings suggest distal adding-on rather than a crankshaft phenomenon around the apex.
- Improved understanding of Shilla mechanics may refine patient and instrumentation level selection.
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