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o-Hydroxycinnamate for sequential photouncaging of two different functional groups and its application in releasing
Amrita Paul1, Manoranjan Bera1, Prakhar Gupta1
1Department of Chemistry, Indian Institute of Technology Kharagpur, 721302, West Bengal, India. ndpradeep@chem.iitkgp.ernet.in.
Abstract:
We demonstrated a new approach for the sequential photouncaging of two different functional groups from o-hydroxycinnamate. The second caged molecule initially remains in the locked state and is released only after attaining its unlocked state upon in situ generation of the second phototrigger, i.e., coumarin, thereby leading to the sequential release of alcohol and carboxylic acid. We have utilised the above strategy for the controlled release of cosmeceutical agents.
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