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Changes in penicillin prescribing in general practice.

F Bro1, C E Mabeck

  • 1Institute of General Practice, University of Aarhus, Denmark.

Danish Medical Bulletin
|June 1, 1988
PubMed
Summary
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Between 1979 and 1983, general practitioners (GPs) reduced phenoxymethyl penicillin use for sinusitis treatment. Conversely, broad-spectrum penicillin prescriptions increased, with no link to doctor seniority or practice conditions.

Area of Science:

  • General Practice
  • Antimicrobial Stewardship
  • Infectious Disease Epidemiology

Background:

  • Sinusitis treatment practices in general practice have evolved.
  • Understanding trends in antibiotic prescribing for sinusitis is crucial for antimicrobial stewardship.
  • Previous research has not fully elucidated changes in penicillin use for sinusitis over time.

Purpose of the Study:

  • To analyze changes in the prescription of phenoxymethyl penicillin versus broad-spectrum penicillin for sinusitis between 1979 and 1983.
  • To investigate the relationship between these prescribing changes and general practitioners' (GPs) seniority and practice conditions.

Main Methods:

  • A longitudinal study analyzing antimicrobial prescriptions for sinusitis.
  • Data collected from GPs across five counties during two specific weeks in 1979 and 1983.

Related Experiment Videos

  • Log-linear analyses used to assess changes in antibiotic use, controlling for covariates.

    • Main Results:

    • A statistically significant decrease in phenoxymethyl penicillin use for sinusitis (odds ratio = 0.84).
    • A statistically significant increase in broad-spectrum penicillin use for sinusitis (odds ratio = 1.18).
    • No significant association found between prescribing trends and GP seniority, practice form, or location.

    Conclusions:

    • The study observed a shift in sinusitis treatment from phenoxymethyl penicillin to broad-spectrum penicillin between 1979 and 1983.
    • Prescribing pattern changes were not influenced by practitioner experience or practice setting.
    • These findings highlight evolving antibiotic prescribing habits in general practice for sinusitis.