Related Experiment Video
Updated: Jan 21, 2026

Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
Published on: March 18, 2014
Photodynamic therapy for basal cell carcinoma of external auditory canal: A case report
Shengjing Xu1, LingLi Zhang2, Min Zhang1
1Department of Dermatology, The Affiliated Jiangning Hospital of Nanjing Medical University, No.168 Gushan Road, Dongshan Street, Jiangning District, 211100, Nanjing, Jiangsu Province, China.
Background:
Basal cell carcinoma (BCC) that occurs in the external auditory canal (EAC) is rare. Currently reported cases are mainly treated with surgical resection. Here, we described an early-detected BCC of the EAC, which achieved good results with photodynamic therapy (PDT).
Methods:
5-aminolevulinic acid (5-ALA) solution was applied on the tumor and its surrounding area of 0.5 cm normal skin. The skin lesion was encapsulated with sterile plastic film and covered with black film to avoid light. Then a special semiconductor laser fiber with 635 nm wavelength red light was directly inserted into the EAC to irradiate the lesion.
Results:
The wound was healed. After 1 year of follow-up, there was no recurrence of the tumor.
Conclusion:
Our case shows that PDT for BCC of the EAC can also achieve good results. It adds a new treatment option for BCC of EAC patients, especially for those who cannot or refuse to use surgery.
Related Concept Videos
Work Done on a System by External Force
In the presence of a non-conservative opposing force, like friction, some part of the work done...
The Auditory Ossicles
The aptly named stapes look very much like a stirrup. The three ossicles are unique to mammals, and each plays a role in...
Laminins are the Adhesive Proteins of Basal Lamina
In humans, the five forms of alpha chains are LAMA 1, LAMA 2, LAMA 3, LAMA 4, and LAMA 5. The four forms of beta chains are LAMB 1, LAMB 2, LAMB 3, and LAMB 4. The three forms of gamma...
Auditory Pathway
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking...
Auditory Perception
Basal Lamina are the Specialized Form of ECM
Proteins...

