The p64 Flow Diverter-Mid-term and Long-term Results from a Single Center.

Area of Science:

• Endovascular neurosurgery
• Cerebrovascular disease management
• Medical device technology

Background:

• Intracranial aneurysms pose significant risks, necessitating effective treatment strategies.
• The p64 flow modulation device is utilized for endovascular aneurysm repair.
• Limited long-term data exists on the p64 device's effectiveness.

Purpose of the Study:

• To evaluate the safety and long-term efficacy of the p64 flow modulation device.
• To assess the device's performance in endovascular treatment of intracranial aneurysms.

Main Methods:

• Retrospective review of a prospectively maintained database (March 2015 - November 2018).
• Inclusion of 72 patients with 72 intracranial aneurysms treated with the p64 device.
• Analysis of anatomical features, procedural complications, and clinical/angiographic outcomes.

Main Results:

• Successful device placement in all 72 patients.
• High complete occlusion rates: 76.3% at 6 months, 91.4% at 12 months, 98.5% at 24 months, and 100% at 36 months.
• Low complication rate: 1.38% permanent morbidity (aneurysmal rupture), 0% mortality, and 2.72% mild intimal hyperplasia.

Conclusions:

• The p64 flow modulation device demonstrates safety and effectiveness for intracranial aneurysm treatment.
• High rates of aneurysm occlusion and infrequent complications support its clinical utility.
• The device offers a successful endovascular option for managing complex cerebrovascular lesions.