Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Bone Matrix01:18

The Bone Matrix

5.5K
Bone contains a relatively small number of cells entrenched in a matrix of collagen fibers that provide an adherent surface for inorganic salt crystals. Both components of the matrix, organic and inorganic, contribute to the unusual properties of bone. Without collagen, bones would be brittle and shatter easily. Without mineral crystals, bones would flex and provide little support. This can be observed by an experiment: when the minerals of a bone are dissolved by soaking the bone in...
5.5K
The Extracellular Matrix01:42

The Extracellular Matrix

88.2K
Overview
88.2K
Golgi Matrix Proteins01:12

Golgi Matrix Proteins

2.4K
Golgi matrix proteins are a group of highly dynamic proteins that maintain the stacked structure of Golgi. These proteins adapt to rapid morphological changes of the Golgi during the cell cycle. During cell division, mild proteolysis removes these connections resulting in Golgi unstacking. In The daughter cells, these proteins help reassemble the unstacked Golgi.
One of the first identified Golgi matrix proteins was GM130, a rod-like protein located in the cis-Golgi. Subsequently, many Golgi...
2.4K
Collagens are the Major Structural Proteins of ECM01:13

Collagens are the Major Structural Proteins of ECM

5.6K
Three main types of fibers are secreted by fibroblasts: collagen fibers, elastic fibers, and reticular fibers. Collagen fiber is made from fibrous protein subunits linked together to form a long, straight fiber. Collagen fibers, while flexible, have great tensile strength, resist stretching, and give ligaments and tendons their characteristic resilience and strength. These fibers hold connective tissues together, even during the body's movement.
Connective tissue proper includes loose...
5.6K
Structural Protein Function01:56

Structural Protein Function

29.8K
Structural proteins are a category of proteins responsible for functions ranging from cell shape and movement to providing support to major structures such as bones, cartilage, hair, and muscles. This group includes proteins such as collagen, actin, myosin, and keratin.
Collagen, the most abundant protein in mammals, is found throughout the body. In connective tissue, such as skin, ligaments, and tendons, it provides tensile strength and elasticity.  In bones and teeth, it mineralizes to...
29.8K
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

773
Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
773

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deep learning-based assessment of periodontitis progression using serial panoramic radiographs: a multicenter study incorporating indirect and direct grading approaches.

Journal of periodontal & implant science·2026
Same author

Development and validation of an early prediction model for bee-sting-induced acute kidney injury using machine learning.

Renal failure·2026
Same author

Efficacy of Submucosal Polydeoxyribonucleotide Injection after Impacted Mandibular Third Molar Extraction: A Randomized Controlled Trial.

Yonsei medical journal·2025
Same author

The Establishment of a Treatment Protocol for the Reconstruction of Mid-Sized Defects in Lip Cancer Using Combinations with the Abbe Flap.

Journal of clinical medicine·2025
Same author

Submental intubation using laparoscopic trocar in zygomaticomaxillary complex fracture surgery in Korea: a case report.

Journal of trauma and injury·2024
Same author

Volumetric analysis of spontaneous bone formation after segmental mandibulectomy in patients with MRONJ.

Oral surgery, oral medicine, oral pathology and oral radiology·2024

Related Experiment Video

Updated: Jan 21, 2026

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.4K

Immediate nonfunctional loading of implants placed simultaneously using computer-guided flapless maxillary crestal

Xueyin An1, Chunui Lee2, Yiqin Fang1

  • 1Department of Dentistry, Yonsei University Wonju College of Medicine, Wonju, South Korea.

Clinical Implant Dentistry and Related Research
|August 13, 2019
PubMed
Summary

This study shows that combining bone morphogenetic protein-2 (BMP-2) with Bio-Oss collagen and immediate non-functional implants in atrophic maxillae leads to excellent bone formation and implant stability.

Keywords:
bone substitutesdental implantimmediate nonfunctional loadingminimal invasive method

More Related Videos

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
11:20

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry

Published on: March 29, 2018

8.0K
Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.4K

Related Experiment Videos

Last Updated: Jan 21, 2026

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy
05:20

Three-Dimensional Collagen Matrix Scaffold Implantation as a Liver Regeneration Strategy

Published on: June 29, 2021

3.4K
Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
11:20

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry

Published on: March 29, 2018

8.0K
Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach
08:01

Designing CAD/CAM Surgical Guides for Maxillary Reconstruction Using an In-house Approach

Published on: August 24, 2018

9.4K

Area of Science:

  • Oral and Maxillofacial Surgery
  • Dental Implantology
  • Regenerative Dentistry

Background:

  • Immediate loading protocols show promise for various forms of edentulism.
  • Limited research exists on bone morphogenetic protein-2 (BMP-2) effects on early bone healing and implant stability, particularly in severely atrophic maxillae.

Purpose of the Study:

  • To assess the impact of immediate non-functional implants and BMP-2-loaded Bio-Oss collagen on bone formation and implant stability.
  • The study focuses on early healing stages in patients with severely atrophic posterior maxillae using a crestal approach.

Main Methods:

  • Thirty-three patients with 1-3 mm residual posterior maxillary bone height underwent flapless crestal sinus augmentation with BMP-2-loaded Bio-Oss collagen.
  • Implants were immediately non-functionally loaded post-surgery.
  • Bone height, density, implant stability (Periotest), and marginal bone loss were evaluated using CBCT and clinical parameters over 37.3 months.

Main Results:

  • Achieved a 100% implant survival rate with healthy peri-implant gingiva.
  • Demonstrated radiographic bone formation in sinus grafts and high bone density.
  • Showed good implant stability and minimal marginal bone loss after 37.3 months.

Conclusions:

  • The described technique is effective for posterior maxillary reconstruction with poor bone quantity.
  • Simultaneous use of BMP-2 loaded graft material and immediate non-functional implant loading is a viable option.