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Updated: Jan 21, 2026

Enhanced Gene Delivery and Expression using Intraosseous Injection of Chitosan Nanoparticles Encapsulated Adenine Base Editor Plasmids
Published on: May 16, 2025
1University of Missouri School of Medicine, Department of Emergency Medicine, Columbia, Missouri.
Improper intraosseous (IO) catheter placement in a cardiac arrest patient led to medication extravasation, causing tissue necrosis and requiring skin grafting. Confirming IO line placement is crucial for patient safety and effective emergency care.
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