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Good outcome of the single-center pediatric kidney transplant program in Abu Dhabi

Gurinder Kumar1, Zubaida AlIsmaili1, Sadia Hafez Ilyas1

  • 1Division of Pediatric Nephrology, Sheikh Khalifa Medical City, Abu Dhabi, United Arab Emirates.

Pediatric Transplantation
|August 14, 2019
PubMed

Insights

Pediatric kidney transplants in the UAE show excellent outcomes. This study highlights high patient and graft survival rates, comparable to international standards, offering improved quality of life for children with end-stage renal disease.

Area of Science:

  • Nephrology
  • Pediatric Surgery
  • Transplantation Immunology

Background:

  • Renal transplantation is the preferred treatment for end-stage renal disease (ESRD) in children, enhancing quality of life, growth, and survival.
  • Evaluating outcomes of pediatric renal transplantation is crucial for improving care in tertiary centers.

Purpose of the Study:

  • To assess the outcomes and complications of pediatric renal transplantation at a tertiary care center in the UAE.
  • To review demographic data, post-transplantation results, and survival rates.

Main Methods:

  • A retrospective chart review of pediatric renal transplants performed between 2010 and 2018.
  • Analysis of surgical complications, infections, graft rejection, graft and patient survival, growth, and estimated glomerular filtration rate (eGFR).

Main Results:

  • Thirty pediatric patients underwent renal transplantation with a mean follow-up of 3.3 years.
  • One and 5-year patient survival rates were 100% and 96.7%, respectively; 1 and 5-year graft survival rates were 96.7% and 83.3%, respectively.
  • Graft rejection occurred in 16.7% of recipients; 70% of recipients were on peritoneal dialysis pre-transplant.

Conclusions:

  • The pediatric kidney transplantation program in the UAE achieved optimal patient and graft survival rates within a 5-year period.
  • Outcomes are comparable to established international centers, demonstrating the program's success.
  • Renal transplantation significantly improves outcomes for children with ESRD.

Keywords:
graft survivalliving donorsoutcomespaediatricsrejection episodesrenal transplantation

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