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Updated: Jan 20, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
Published on: December 5, 2015
Gestational weight management and pregnancy outcomes among women of advanced maternal age
Juan Lin1, Yuelin Fu1, Qing Han1
1Department of Obstetrics, Fujian Provincial Maternity and Children's Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian 350001, P.R. China.
Abstract:
In this study, we assessed the effects of pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on the pregnancy outcomes of women of advanced age using a back-propagation (BP) artificial neural network. We conducted a retrospective analysis on postpartum and hospital delivery data from 1,015 women of advanced maternal age (AMA) hospitalized at the Fujian Provincial Maternity and Children's Hospital from January to June, 2017. Pre-pregnancy overweight was found to increase the incidence of gestational diabetes mellitus (GDM), hypertensive disorders complicating pregnancy (HDCP) and fetal macrosomia. In addition, poor weight gain during pregnancy increased the chances of pre-term births (PTBs). Furthermore, excessive weight gain during pregnancy increased the incidence of macrosomia in women of AMA. On the whole, the findings of this study suggest that controlling the pre-pregnancy BMI and the GWG may reduce the incidence of adverse pregnancy outcomes in women of AMA. The BP neural network is suitable for the study of weight changes in this population.
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