Related Experiment Video
Updated: Jan 20, 2026

07:56
Closed Chest Biventricular Pressure-Volume Loop Recordings with Admittance Catheters in a Porcine Model
Published on: May 18, 2021
4.2K
Suboptimal biventricular pacing. What is the mechanism?
Vern Hsen Tan1, Colin Yeo1, Kelvin Wong1
1Cardiology Department Changi General Hospital Singapore Singapore.
Journal of Arrhythmia
|August 15, 2019
Summary
Suboptimal biventricular pacing can harm patients undergoing cardiac resynchronization therapy. This case study details a unique instance of pacing issues and the successful strategy implemented to resolve them.
Area of Science:
- Cardiology
- Medical Devices
Background:
- Cardiac resynchronization therapy (CRT) aims to improve heart function through synchronized ventricular pacing.
- Suboptimal biventricular pacing, where the electrical signals do not coordinate the ventricles effectively, can lead to adverse outcomes.
Observation:
- A unique case of suboptimal biventricular pacing was identified in a patient receiving CRT.
- This specific instance presented challenges in achieving optimal ventricular synchrony.
Findings:
- The study details the specific characteristics of the suboptimal biventricular pacing observed.
- A novel approach was developed and implemented to address and overcome the identified pacing inefficiencies.
Implications:
- Successfully overcoming suboptimal biventricular pacing can improve CRT efficacy.
- This case highlights the importance of tailored strategies for optimizing device performance in complex patient scenarios.
Related Concept Videos
Reaction Mechanisms
30.5K
Chemical reactions often occur in a stepwise fashion, involving two or more distinct reactions taking place in a sequence. A balanced equation indicates the reacting species and the product species, but it reveals no details about how the reaction occurs at the molecular level. The reaction mechanism (or reaction path) provides details regarding the precise, step-by-step process by which a reaction occurs.
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
For instance, the decomposition of ozone appears to follow a mechanism with two steps:
30.5K
Mechanical Protein Functions
5.5K
Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force.
5.5K
Mechanism of Conjugation
870
Bacterial conjugation is a mechanism of horizontal gene transfer that enables the exchange of genetic material between bacterial cells through direct contact. This process is facilitated by a donor cell carrying a conjugative plasmid, which encodes genes necessary for pilus formation, DNA replication, and transfer. The conjugative plasmid plays a central role in initiating and executing the transfer of genetic material.The tra region of the conjugative plasmid encodes proteins responsible for...
870
Mechanical Systems
594
Mechanical systems are analogous to to electrical networks where springs and masses play similar roles to inductors and capacitors, respectively. A viscous damper in mechanical systems functions similarly to a resistor in electrical networks, dissipating energy. The forces acting on a mass in such systems include an applied force in the direction of motion, counteracted by forces from the spring, a viscous damper, and the mass's acceleration. This interplay of forces is mathematically...
594
Compensation Mechanisms
1.9K
The human body employs intricate mechanisms to counteract changes in blood pH, preventing conditions like acidosis (pH < 7.35) and alkalosis (pH > 7.45). These compensatory responses aim to restore normal arterial blood pH by engaging respiratory or renal systems, depending on the source of the imbalance.
Respiratory Compensation
This mechanism addresses metabolic-induced pH imbalances by adjusting breathing rates. Respiratory compensation begins within minutes of detecting a pH...
Respiratory Compensation
This mechanism addresses metabolic-induced pH imbalances by adjusting breathing rates. Respiratory compensation begins within minutes of detecting a pH...
1.9K
An Introduction to Mechanics
7.1K
Humans have been making ships, shelters, pyramids, weapons, agricultural equipment, and many more items without recording the process or theory behind them for centuries. It would be challenging to document the evolution of mechanics from its origin to the present.
According to records, the history of mechanics starts with Aristotle (384–322 BC). He related mechanics to physical theory, aiming for a universal synthesis.
Newton defined mechanics as the branch of physical science that...
According to records, the history of mechanics starts with Aristotle (384–322 BC). He related mechanics to physical theory, aiming for a universal synthesis.
Newton defined mechanics as the branch of physical science that...
7.1K

